The Blotworx were created by the Mad Doctor initially to serve as a new army to get revenge, but they were deemed unpredictable and he spread them throughout Wasteland. They are piloted by cycloptic Spatters forced to do so.
Types of Blotworx
Blockers are the most common type of Blotworx in Epic Mickey 2: The Power of Two. Their name is inspired by the red force field they activate from their left arm to protect themselves from Mickey's attacks. Their appearance is that of V.I.N.CENT from The Black Hole, a little red robot with white eyes, a pincer-like left arm and a wrecking ball on the right arm. They attack by swinging the iron ball attached to their right arm.
Rockers are a semi-common variety of Blotworx in Epic Mickey 2: The Power of Two, often noted as the most formidable. Their namesake is their constant rocking motion as they move. Being vehicles, they can run down Mickey or Oswald and knock them aside, but their most powerful weapons are rocket-shaped homing missiles that seek you out. Their appearance suggests they are a cross between a car and a unicycle, though concept art shows they were originally modelled after Herbie, the car from The Love Bug.
Shockers are the strongest, but least common, type of Blotworx in Epic Mickey 2: The Power of Two. They are huge Blotworx that attack in various ways using their fists and electricity, the latter method being their namesake. Their appearance is composed of various thing from Atlantis: The Lost Empire, as well as its sequel.
- The Blotworx are defeated by when Oswald zaps one with electricity a blotling will come out look around. While he is looking around Mickey can spray paint or thinner him like he would do with a regular Blotling which will make him friendly if Mickey and Oswald continue this pattern the blotling inside will become friendly if you paint and the Blotworx will help you. If you decide to thin the Blotling, the Blotworx will break down and explode.
- In an original script, Gremlin Prescott was to be thrown off a cliff by them. 
- The Blotworx's role in Epic Mickey 2: The Power of Two — The Graphic Novel is very small; the only one that is really seen at all is the Blotworx Dragon, though the Mad Doctor claims that there are others out there.